Hepatitis C elimination: challenges with under-diagnosis and under-treatment
نویسندگان
چکیده
منابع مشابه
Hepatitis C: diagnosis and treatment.
Hepatitis C, a common chronic bloodborne infection, is found in approximately 2 percent of adults in the United States. Chronic infection is associated with serious morbidity and mortality (e.g., cirrhosis, hepatocellular carcinoma). Testing for hepatitis C is recommended for at-risk populations, and confirmatory testing includes quantification of virus by polymerase chain reaction. The U.S. Pr...
متن کاملHepatitis B Virus Reactivation under Treatment with Nilotinib
Hepatitis B virus (HBV) reactivation with imatinib, a tyrosine kinase inhibitor, has been reported in chronic myeloid leukemia. Nilotinib is a more potent second generation tyrosine kinase inhibitor and it inhibits the Src-family kinase LCK and hamper proliferation and function of CD8 (+) T lymphocytes. CD8 (+) T lymphocytes are the main cellular subset responsible for viral clearance in patien...
متن کاملestimation of average diagnosis and treatment costs of hepatitis c
aim : the objective of this study was to estimate the average cost of diagnosis and treatment of hepatitis c among patients based on their treatment regime, during the one course of treatment and six-month after stopping that. background : hepatitis c virus (hcv) infection is a major cause of liver-related morbidity and mortality worldwide and a major public health problem. patients and methods...
متن کاملThe Effect of Shorter Treatment Regimens for Hepatitis C on Population Health and Under Fixed Budgets
Background Direct acting antiviral hepatitis C virus (HCV) therapies are highly effective but costly. Wider adoption of an 8-week ledipasvir/sofosbuvir treatment regimen could result in significant savings, but may be less efficacious compared with a 12-week regimen. We evaluated outcomes under a constrained budget and cost-effectiveness of 8 vs 12 weeks of therapy in treatment-naïve, noncirrho...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: F1000Research
سال: 2019
ISSN: 2046-1402
DOI: 10.12688/f1000research.15892.1